Fatal liver necrosis associated with the use of nitrofurantoin.
نویسندگان
چکیده
منابع مشابه
Biol. Pharm. Bull. 28(11) 2155—2157 (2005)
sources, it is important that relevant models of human liver toxicosis are used in order to identify agents with therapeutic potential. Thus, we considered the use of hepatotoxic agents relevant to human liver toxicosis in assay protocols. Examples of such hepatotoxic agents include pharmaceutical agents like tacrine and nitrofurantoin. Tacrine (1,2,3,4tetrahydro-9-aminoacridine hydrochloride) ...
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Background: Hepatitis activity index (HAI) and fibrosing stage are two important findings during the evaluation of liver samples in patients with chronic hepatitis B. The aim of this study was to determine the HAI and fibrosing stage in patients with anti-HBe positive chronic hepatitis B. Methods: Liver biopsy slides of 72 patients were evaluated at the Department of Pathology in two teaching ...
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The spectrum of nitrofurantoin lung injury continues to widen. The case histories are presented of two patients who developed lung disease associated with the use of nitrofurantoin with histological features of bronchiolitis obliterans organising pneumonia (BOOP), a rare but recognised form of drug induced injury. The two middle aged women presented with respiratory symptoms after prolonged tre...
متن کاملBronchiolitis obliterans organising pneumonia associated with the use of nitrofurantoin.
The spectrum of nitrofurantoin lung injury continues to widen. The case histories are presented of two patients who developed lung disease associated with the use of nitrofurantoin with histological features of bronchiolitis obliterans organising pneumonia (BOOP), a rare but recognised form of drug induced injury. The two middle aged women presented with respiratory symptoms after prolonged tre...
متن کاملNitrofurantoin-induced chronic active hepatitis.
BACKGROUND Nitrofurantoin is a commonly prescribed urinary antiseptic. Hepatic injury has been associated with its use. OBJECTIVES To present three patients in whom long-term exposure to the drug resulted in chronic active hepatitis; and to review the epidemiology, clinical immunology, histopathology, pathogenetic features and treatment of previously reported cases. RESULTS Withdrawing nitr...
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عنوان ژورنال:
- The Israel Medical Association journal : IMAJ
دوره 3 5 شماره
صفحات -
تاریخ انتشار 2001